Fermentation Vessels
FERMENTATION VESSELS
Fermentation Vessels manufactured by Neelam industries are the most flexible designed product to meet the requirements of the Pharmaceutical Industry.
Fermentation Vessels
Technical Specifications
- Capacity : 4-5 KL
- Filling Volume : 65-80%
- Material : Wetted parts are SS316L, and others is SS304
- Surface Finish : inside surface is 0.28-0.6µm by electro Poloshoutside surface is 0.4-0.8µm by satin finish.
- Agitation
- Fermentor use SEW / Bonfigloli decelerator
- top mechanical agitator with two layer six blade impeller, one layer defoamer and four baffles.
- mechanical seal (single or double mechanical seal)
- speed range: 50-400rpm (it depends on the size of the vessel)
Or
Bottom mounted Magnetic mixer with speed variation from 20 to 400 RPM
- Equips of vessel
- using alcohol flame inoculation
- sterilisable sampling and Flush bottom valve
- CIP & SIP system inbuilt.
- PH, DO, temp. sensor on lower side, side glass, top with foam and level probe, and 12v sight glass with lamp, etc.
- Construction : Floor-type One fermentor vessel with one control system
Main components and controls of system
- PH :
- On-line check and measure, and digitization fully automatic control
- PH, acid and base gang control. Peristatic pump automatically adjust to feed acid and base
- Control range 2-12pH, measure precision±0.01 pH, control precision±0.1 pH
- It has auto alarm function
- pH sensor and signal transmission line, Mettler toledo
- Do :
- On-line check and measure, cascade with rpm; digital display.
- Range 0-100% or 0-200%, precision ±1%;
- It has auto alarm function
- DO sensor and signal transmission line, Mettler toledo
- Foam control :
- Automatically control and automatically alarm
- Stainless steel electrode check, peristaltic pump automatically add defoamer.
- Feed control :
- Automatically control and automatically alarm
- Stainless steel electrode check, peristaltic pump automatically feeding
- Temp. control :
- PID fully digitization signal processing, digitization control settings
- Circulating water automatically control temperature
- Measure range 0-150degree, control range 15- 45degree,control precision±0.2degree
- Pt 100 O temp. Sensor
- system with electrical heater to control the temp inside vessel
- water pump circulation
- solenoid valve to control
- Rotate speed :
- Automatically control , with auto alarm function
- Siemens frequency converter to adjust the speed
- Pressure :
- Manually adjusting with pressure gauge and manual valve (standard system)
- Automatically adjusting with pressure transmitter and PID valve and pneumatic valves (optional)
- Air flow :
- Manually adjusting with rotor meter and manual valve (standard system)
- Automatically adjusting with mass-flow meter and pneumatic valves (optional)
- Air in filter , tail gas filter , with PALL cartridge, precision 0.2µm
- Sterilization :
- Fermentation vessel can be SIP by connecting with steam
- Automatic control with pneumatic valves
- Control : B&R AUSTRIA PLC, and B&R 10.4” touch screen(HMI) and NEELAM INDUSTRIES program
AUTOMATION :
In compliance with :
cGMP, GAMP, ISO 9001 : 2008